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| Product Name | trans-Urocanic Acid |
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| Description | Purity >98%. trans -Urocanic acid is a major epidermal chromophore for the immunosuppressive effects of UV radiation that is produced in mammalian stratum corneum by the action of histidine ammonialyase on L-histidine. It contributes to the acidification of the surface of the stratum corneum, and its function has been proposed as that of an endogenous sunscreen, endowing a low-level of protection (SPF ~ 1.5) against UV-induced DNA damage and excessive keratinocyte apoptosis. Upon UVB exposure, trans -urocanic acid is converted to the cis isomer, which is known to activate regulatory T cells. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-(1H-imidazol-5-yl)-2E-propenoic acid |
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| Gene, Accession, CAS # | CAS: 3465-72-3 |
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| Catalog # | LS-H10283 |
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| Order / More Info | trans-Urocanic Acid from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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