产品详情 |
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Product Name | P1075 |
Description | A potent activator of SUR2-Kir6 and KATP channels; activates SUR2-Kir6 channels (EC50 = 45 nM for SUR2B-Kir6 channel activation); highly selective for SUR2 over SUR1 isoforms (IC50s = 9-46 nM and 1.02 mM, respectively, in a radioligand binding assay); increases outflow facility, a marker of reduced intraocular pressure, in human eye anterior segments ex vivo; reduces infarct size in isolated rabbit hearts via activation of mitochondrial KATP channels (EC50s = 60-90 nM) |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | P-1075 SUR-1 2 2B SUR2Kir6 SUR2BKir6 |
Gene, Accession, CAS # | CAS: 60559-98-0 |
Catalog # | 21849-1 |
Price | |
Order / More Info | P1075 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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