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| Product Name | Sphingosine-1-Phosphate |
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| Description | Purity >98%. Sphingosine-1-phosphate (S1P) is the product of phosphorylation of sphingosine by sphingosine kinase. Like many products of sphingomyelin, it exhibits a wide range of biological activities. Not only does it enhance cell growth, but it can inhibit the normal apoptotic response to a variety of stimuli. The ability of PKC to block apoptosis is likely due to the formation of S1P. S1P stimulates MAPK and counteracts the ceramide-induced activation of SAPK and JNK. It also increases intracellular calcium levels by both the liberation of calcium from internal stores3 and through activation of a Gi protein-coupled receptor resulting in the opening of a cell surface calcium channel. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2S-amino-4E-octadecene-1,3R-diol 1-(dihydrogen phosphate), S1P (d18:1), Sphingosine-1-Phosphoric Acid |
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| Gene, Accession, CAS # | CAS: 26993-30-6 |
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| Catalog # | LS-H9995 |
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| Order / More Info | Sphingosine-1-Phosphate from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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