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Product Name | Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 63-148) (Active) protein |
Description | Proheparin-binding EGF-like growth factor (HB-EGF), also known as DTR, DTS and HEGFL, is a member of the EGF family of mitogens. It is expressed in macrophages, monocytes, endothelial cells and muscle cells. HB-EGF signals through the EGF receptor to stimulate the proliferation of smooth muscle cells, epithelial cells and keratinocytes. Compared to EGF, HB-EGF binds the EGF receptor with higher affinity and is thus more mitogenic, probably due to its ability to bind to heparin and heparin sulfate proteoglycans. HB-EGF has been reported to act as a diphtheria toxin receptor, mediating endocytosis of the bound toxin.Synonyms: DTR, DTS, HEGFL |
Size | 25 µg |
Concentration | n/a |
Applications | n/a |
Other Names | hbegf|zgc:165443|HBEGF|zgc:175091|DTR|DTS|DTSF|HEGFL|Dtr|GFHB|Hb-egf|Hegfl|AW047313|Dts|HB-EGF |
Gene, Accession, CAS # | n/a |
Catalog # | ABIN2018330 |
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Order / More Info | Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 63-148) (Active) protein from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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