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| Product Name | Recombinant Human Ribonucleoside-diphosphate reductase subunit M2 B (RRM2B) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 67.7kDa. Full Length: 1-351aa. N-terminal GST-tagged. Homo sapiens (Human). Plays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner. Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2. Contains an iron-tyrosyl free radical center required for catalysis. Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | TP53-inducible ribonucleotide reductase M2 B; p53-inducible ribonucleotide reductase small subunit 2-like protein |
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| Gene, Accession, CAS # | RRM2B, UniProt: Q7LG56 |
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| Catalog # | RPC23204 |
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| Order / More Info | Recombinant Human Ribonucleoside-diphosphate reductase subunit M2 B (RRM2B) from BIOMATIK |
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| Product Specific References | n/a |
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