| 产品详情 |
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| Product Name | TAK-875 |
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| Description | Purity >94%. The free fatty acid receptor 1 (FFAR1; GPR40) is highly expressed in pancreatic beta -cells and activated by medium and long-chain fatty acids. There is evidence of a link between FFAR1 (GPR40) and the ability of fatty acids to amplify glucose-stimulated insulin secretion, making this signaling pathway a potential target for regulating diabetes, obesity, and other metabolic disorders. TAK-875 is a selective FFAR1 (GPR40) agonist (EC50 = 26 nM) that does not exhibit activity on the related FFARs FFAR2 (GPR43) or FFAR3 (GPR41). |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (3S)-6-[[2',6'-dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl]methoxy]-2,3-dihydro-3-benzofuranacetic acid |
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| Gene, Accession, CAS # | CAS: 1000413-72-8 |
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| Catalog # | LS-H136 |
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| Order / More Info | TAK-875 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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