| 产品详情 |
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| Product Name | Osthole |
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| Description | Purity >98%. Osthole is a natural coumarin that was first isolated from several medicinal plants, including C. monnieri and A. pubescens . It is reported to induce a nonspecific elevation of cAMP and cGMP levels through its ability to inhibit phosphodiesterases, which leads to a modulation of calcium channel signaling and vasorelaxant effects. Osthole exhibits immunomodulatory, antioxidative, and anti-inflammatory properties, by regulating the expression of TNF-Alpha, NF-?B, TGF-Beta, cyclooxygenases, leukotrienes, nitric oxide, ERK, and JNK. It also demonstrates antifibrotic effects in both hepatic and myocardial tissues and has been suggested to be a natural activator of defective delta F508-cystic fibrosis transmembrane conductance regulator chloride channel gating. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 7-methoxy-8-(3-methyl-2-buten-1-yl)-2H-1-benzopyran-2-one, 7-Methoxy-8-(3-methyl-2-butenyl)coumarin, NSC 31868 |
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| Gene, Accession, CAS # | CAS: 484-12-8 |
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| Catalog # | LS-H9209 |
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| Price | |
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| Order / More Info | Osthole from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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