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| Product Name | Recombinant Mouse Prolactin protein (Prl) (Active) |
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| Description | Purity > 85% as determined by SDS-PAGE. MW: 52.3kDa. Full Length of Mature Protein: 2-223aa. N-terminal GST-tagged. Homo sapiens (Human). Distributive alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and mono- or di-methylation of Pro in the Pro-Pro-Lys motif. Some of the substrates may be primed by METTL11B-mediated monomethylation. Responsible for the N-terminal methylation of KLHL31, MYL2, MYL3, RB1, RCC1, RPL23A and SET. Required during mitosis for normal bipolar spindle formation and chromosome segregation via its action on RCC1. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Alpha N-terminal protein methyltransferase 1AMethyltransferase-like protein 11AN-terminal R; CC1 methyltransferaseX-Pro-Lys N-terminal protein methyltransferase 1A; NTM1A |
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| Gene, Accession, CAS # | NTMT1, UniProt: Q9BV86 |
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| Catalog # | RPC27050 |
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| Order / More Info | Recombinant Mouse Prolactin protein (Prl) (Active) from BIOMATIK |
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| Product Specific References | n/a |
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