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| Product Name | QNZ |
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| Description | Purity >98%. Nuclear factor-?B (NF-?B) is an ubiquitous transcription factor that functions to enhance the transcription of pro-inflammatory cytokines like TNF-Alpha, IL-1Beta, IL-6, and IL-8. QNZ is an inhibitor of NF-?B activation with an IC50 of 11 nM in human Jurkat cells. It also inhibits TNF-Alpha production from lipopolysaccharide-stimulated mouse splenocytes with an IC50 of 7 nM. QNZ showed efficacy in vivo by reducing edema formation in carrageenin-induced inflammation of rat hind paw. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N4-[2-(4-phenoxyphenyl)ethyl]-4,6-quinazolinediamine, CAY10470 |
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| Gene, Accession, CAS # | CAS: 545380-34-5 |
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| Catalog # | LS-H9617 |
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| Order / More Info | QNZ from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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