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| Product Name | Calbindin 1, 28kDa (CALB1) (AA 1-261) protein |
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| Description | Calbindin 1 (CALB1) is a calcium binding protein that is a member of the troponin C superfamily. CALB1 plays a vital role in calcium regulation (including calcium transport and uptake, calcification of bone and teeth) and calcium associated signaling in neurons and transiently in embryological development. CALB1 also has a role in protecting neurons from apoptotic cell death. CALB1 buffers cytosolic calcium and may stimulate a membrane Ca2+-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase. The biological function of CALB1 seems to be tied to the redox state of its five cysteine residues.CALB1 has 4 active calcium-binding domains, and 2 modified domains that seemingly have lost their calcium-binding ability. CALB1 is expressed in neural tissues. In the brain, the CALB1 synthesis is independent of vitamin-D-derived hormones. Disregulation of the CALB1 is associated with epilepsy, amyotrophic lateral sclerosis, Huntington's disease. The neurons in brains of Huntington disease patients are calbindin-depleted Synonyms: Calbindin, Vitamin D-dependent calcium-binding protein, avian-type, Calbindin D28, D-28K, CALB1, CAB27, CALB, calbindin 1 20 kDa |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CG6702|Calb|Cbp33|DCBP|Dcbp|Dcp|Dmel\\CG6702|cbn|cbp53E|CALB1|calb1|CaBP28K|CB|Calb-1|Brain-2|CALB|Calbindin |
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| Gene, Accession, CAS # | Gene ID: 793 |
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| Catalog # | ABIN807558 |
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| Order / More Info | Calbindin 1, 28kDa (CALB1) (AA 1-261) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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