| 产品详情 |
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| Product Name | S32826 |
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| Description | Purity >98%. Autotaxin is a lysophospholipase D, cleaving lysophosphatidylcholine to produce choline and lysophosphatidic acid (LPA). S32826 is a potent and selective inhibitor of autotaxin, inhibiting recombinant autotaxin Beta with an IC50 of 8.8 nM. It shows similar effectiveness against the three known autotaxin isoforms (Alpha, Beta, and Gamma). It has no effect on a variety of receptors and enzymes, with the exceptions of src (IC50 = 6 µM) and phosphatase 1B (IC50 = 15 µM). S32826 inhibits LPA release from adipocytes (IC50 = 90 nM) and reduces plasma autotaxin activity by 57% when used at 5 µM. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | P-[[4-[(1-oxotetradecyl)amino]phenyl]methyl]-phosphonic acid |
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| Gene, Accession, CAS # | CAS: 1096770-84-1 |
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| Catalog # | LS-H9803 |
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| Price | |
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| Order / More Info | S32826 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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