| 产品详情 |
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| Product Name | AdipoRon |
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| Description | Purity >98% by NMR, TLC. AdipoRon is a novel potent and selective adiponectin (AdipoR1 and AdipoR2) receptor agonist, Kd=1.8 and 3.1 uM respectively. Displayed similar effects to adiponectin in muscle and liver such as activation of PPARa and AMPK signaling pathways. It also reversed insulin resistance and glucose intolerance in mice on a high-fat diet. AdipoRon ameliorated diabetes in a genetically obese mouse model and prolonged the shortened lifespan of db/db mice on a high-fat diet. Attenuates PDGF-induced VSMC proliferation via inhibition of mTPR signaling in an AMPK independent manner. Active in vivo. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-(4-Benzylphenoxy)-N-(1-benzylpiperidin-4-yl)acetamide |
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| Gene, Accession, CAS # | CAS: 924416-43-3 |
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| Catalog # | LS-H14584 |
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| Order / More Info | AdipoRon from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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