| 产品详情 |
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| Antigenic Specificity | CD271 (p75NTR) |
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| Clone | NGFR5 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | IHC-P |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-human CD271 (p75NTR). CD271, also known as p75NTR, TNFRSF16, p75(NTR), Gp80-LNGFR, and NGFR, is a type I transmembrane protein with a MW of 75 kD. It is expressed by many cell types including neurons, Schwann cells, mesenchymal stem/stromal cells, follicular dendritic cells and melanocytes. The extracellular portion contains four TNFR-Cys repeats that form the binding domain for its ligands (NGF, BDNF, NTF3, and NTF4). The intracellular portion of CD271 contains a death domain, which interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9, to promote cell apoptosis and to regulate cell differentiation and neurogenesis. |
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| Immunogen | This monoclonal antibody was raised against A875 human myeloma cells and p75NTR purified from A875 human myeloma cells. |
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| Other Names | Tumor necrosis factor receptor superfamily member 16, p75 ICD, NGF receptor, TNFR superfamily, member 16, low affinity nerve growth factor receptor, low affinity neurotrophin receptor p75NTR, low-affinity nerve growth factor receptor, CD271, p75NTR, TNFRSF16, p75(NTR), Gp80-LNGFR, MMS-5228-100 |
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| Gene, Accession # | Gene ID: 4804 |
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| Catalog # | 818201 |
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| Price | |
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| Order / More Info | CD271 (p75NTR) Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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