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| Product Name | Cadherin 11 (C-Term), (AA 23-617) protein |
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| Description | Recombinant Human Cadherin 11 Type 2 OB-Cadherin (Osteoblast)/CDH11 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Phe23-Thr617) of Human CDH11 fused with a polyhistidine tag at the C-terminus. Cadherin-11 is a type II classical cadherin member of the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherins interact with themselves in a homophilic manner in connecting cells, and thus contribute to the sorting of heterogeneous cell types. Cadherin-11 contains five cadherin domains and is mainly expressed in the brain. Mature cadherin proteins consists of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small highly conserved C-terminal cytoplasmic domain. It is shown that Cadherin-11 is a viable molecular target for therapeutic intervention in Glioblastoma multiforme. |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | cad11|cdhob|osf-4|Xcad-11|MGC108014|OB-cadherin|cadherin-11|Cad11|cdhvn|vnc|CAD11|CDHOB|OB|OSF-4 |
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| Gene, Accession, CAS # | Gene ID: 1009 |
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| Catalog # | ABIN1691422 |
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| Order / More Info | Cadherin 11 (C-Term), (AA 23-617) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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