| 产品详情 |
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| Antigenic Specificity | CCR6, aa18-46 |
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| Clone | polyclonal |
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| Host Species | Goat |
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| Reactive Species | mouse, human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | ELISA (1:35000), IHC, IHC-P (5 µg/ml), WB (1:250) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CCR6 Antibody (aa18-46) LS-C187844. Recognizes human CD196, otherwise known as CCR6 (C-C chemokine receptor type 6), a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, which acts as a specific receptor for the C-C chemokine LARC (Liver and activation-regulated chemokine)/MIP-3alpha, a selective chemoattractant which induces calcium flux in CD196-expressing lymphocytes. CD196 is preferentially expressed by B cells, memory T cells and immature dendritic cells and plays an important role in B lineage maturation and antigen-driven B cell differentiation. CD196 acts as a co-receptor for HIV1 infection, and is selectively expressed by mucosa-associated non-Hodgkin's lymphoma, making the interaction between CD196 and LARC a potential therapeutic target in these malignancies. Cross-reacts with mouse CD196, where linear epitopes are accessible. |
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| Immunogen | Synthetic peptide YFVSVNTSYYSVDSEMLLCSLQEVRQFSR corresponding to amino acids 18-46 of human CD196. Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon (100%); Chimpanzee (97%); Monkey (86%). |
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| Other Names | CCR6, C-c chemokine receptor 6, CD196 antigen, BN-1, C-C chemokine receptor type 6, C-C CKR-6, Chemokine c-c motif receptor 6, CKRL3, CMKBR6, Chemokine (C-C) receptor 6, Chemokine receptor-like 3, Cc chemokine receptor 6, CC-CKR-6, CCR-6, DCR2, DRY6, G protein-coupled receptor 29, DRY-6, G-protein coupled receptor 29, GPR29, GPRCY4, Strl-22, STRL22, CD196, CKR-L3, GPR-CY4, LARC receptor |
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| Gene, Accession # | CCR6, Gene ID: 1235 |
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| Catalog # | LS-C187844 |
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| Price | |
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| Order / More Info | CCR6, aa18-46 Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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