| 产品详情 |
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| Antigenic Specificity | DDX5 |
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| Clone | 14B9A58 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse |
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| Isotype | IgG2b, κ |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blot (WB), ICC |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-DDX5. DDX5, also named RNA helicase p68, is a prototypic member of the DEAD (Asp-Glu-Ala-Asp) box family. DDX5 has been shown to be involved in the processes requiring the alteration of RNA structures, such as the maturation of pre-mRNA, rRNA, and miRNA. DDX5 also plays important helicase-independent roles in transcriptional regulation. DDX5 can act as a transcriptional coactivator of the androgen receptor (AR), estrogen receptor α (ERα), tumor suppressor p53, MyoD, RUNX2, and β-catenin, which are involved in the regulation of cell proliferation, differentiation, and tumorigenesis. DDX5 has been shown to be up-regulated in various cancers, including breast cancer, prostate cancer, and colorectal cancer, suggesting that DDX5 may participate in tumor development. DDX5 can also act as a transcriptional repressor through interacting with HDAC1. |
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| Immunogen | Partial human DDX5 recombinant protein (482-614 a.a.) expressed in E. coli. |
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| Other Names | Probable ATP-dependent RNA helicase DDX5, DEAD box protein 5, RNA helicase p68 |
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| Gene, Accession # | Gene ID: 1655 |
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| Catalog # | 661302 |
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| Price | |
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| Order / More Info | DDX5 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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| 产品资料 |
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