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Antigenic Specificity | Exportin 1/CRM1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | Alexa Fluor® 350 conjugate |
Size | 100ul |
Concentration | 1ug/ul |
Applications | IF(IHC-P) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Exportin 1/CRM1 Polyclonal Antibody, Alexa Fluor® 350 Conjugated. • Target Background: Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of RNAs. In the nucleus, in association with RANBP3, binds cooperatively to the NES on its target protein and to the GTPase RAN in its active GTP-bound form (Ran-GTP). Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP |
Immunogen | KLH conjugated synthetic peptide derived from human Exportin 1/CRM1. Immunogen Range: 720-770/1071 |
Other Names | emb; CRM1; exp1; Exportin-1; Chromosome region maintenance 1 protein homolog; XPO1 |
Gene, Accession # | Gene ID: 7514, SwissProt: O14980 |
Catalog # | bs-10151R-A350 |
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Order / More Info | Exportin 1/CRM1 Antibody from BIOSS ANTIBODIES |
Product Specific References | n/a |
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