| 产品详情 |
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| Antigenic Specificity | Nkx2.5 |
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| Clone | 4B11 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2b, kappa |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | ELISA: Assay-Dependent, Immunoprecipitation: Assay-Dependent, Western Blot: 1-5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Nkx2.5 Monoclonal Antibody (4B11). Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development (Shiojima et al., 1995 [PubMed 7665173]). It has been demonstrated that a Drosophila homeobox-containing gene called 'tinman' is expressed in the developing dorsal vessel and in the equivalent of the vertebrate heart. Mutations in tinman result in loss of heart formation in the embryo, suggesting that tinman is essential for Drosophila heart formation. Furthermore, abundant expression of Csx, the presumptive mouse homolog of tinman, is observed only in the heart from the time of cardiac differentiation. CSX, |
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| Immunogen | n/a |
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| Other Names | CHNG5, CSX, CSX1, HLHS2, NKX2.5, NKX2E, NKX4-1, VSD3, NK2 transcription factor related, locus 5, cardiac-specific homeobox 1, homeobox protein CSX, homeobox protein NK-2 homolog E, homeobox protein Nkx-2.5, tinman paralog |
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| Gene, Accession # | Entrez: 1482; Uniprot: P52952 |
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| Catalog # | MA5-18671 |
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| Price | |
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| Order / More Info | Nkx2.5 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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