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| Product Name | Interleukin 3 (Colony-Stimulating Factor, Multiple) (Il3) (AA 20-152) (Active) protein |
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| Description | Interleukin-3 (IL-3) is a pleiotropic cytokine belonging to the interleukin family. IL-3 shares similarities with Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) and IL-5: they all have a four-helix bundle structure, are located on the same chromosomes in both human and mouse, are produced by activated T cells, and share receptors. The IL-3/IL-5/GM-CSF receptor family members are all heterodimeric, composed of a receptor-specific alpha chain and a common beta chain. IL-3 is also called multi-colony stimulating factor since it stimulates the development and colony formation of multiple lineages of hematopoietic cells by activating intracellular pathways such as Ras-Raf-ERK and JAK/STAT. IL-3 inhibits apoptosis and promotes cell survival by targeting the anti-apoptotic bcl-2 gene family. Recombinant human Interleukin-3 (rhIL-3) produced in E. coli is a single non-glycosylated polypeptide chain containing of 134 amino acids. A fully biologically active molecule, rhIL-3 has a molecular mass of 15.2 kDa analyzed by non-reducing SDS-PAGE. Synonyms: MCGF (Mast cell growth factor), Multi-CSF, HCGF, P-cell stimulation factor |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | BPA|Csfmu|HCGF|Il-3|MCGF|PSF|IL-3|MULTI-CSF |
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| Gene, Accession, CAS # | Gene ID: 3562 |
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| Catalog # | ABIN2018100 |
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| Order / More Info | Interleukin 3 (Colony-Stimulating Factor, Multiple) (Il3) (AA 20-152) (Active) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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