| 产品详情 |
| Edit |   |
|---|
| Product Name | Interleukin 3 (Colony-Stimulating Factor, Multiple) (Il3) (AA 33-166) (Active) protein |
|---|
| Description | Interleukin-3 (IL-3) is a pleiotropic cytokine belonging to the interleukin family. IL-3 shares similarities with Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) and IL-5: they all have a four-helix bundle structure, are located on the same chromosomes in both human and mouse, are produced by activated T cells, and share receptors. The IL-3/IL-5/GM-CSF receptor family members are all heterodimeric, composed of a receptor-specific alpha chain and a common beta chain. IL-3 is also called multi-colony stimulating factor since it stimulates the development and colony formation of multiple lineages of hematopoietic cells by activating intracellular pathways such as Ras-Raf-ERK and JAK/STAT. IL-3 inhibits apoptosis and promotes cell survival by targeting the anti-apoptotic bcl-2 gene family. Recombinant mouse Interleukin-3 (rmIL-3) produced in E. coli is a single non-glycosylated polypeptide chain containing of 135 amino acids. A fully biologically active molecule, rmIL-3 has a molecular mass of 15.2 kDa analyzed by non-reducing SDS-PAGE. Synonyms: MCGF (Mast cell growth factor), Multi-CSF, HCGF, P-cell stimulation factor |
|---|
| Size | 50 µg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | BPA|Csfmu|HCGF|Il-3|MCGF|PSF|IL-3|MULTI-CSF |
|---|
| Gene, Accession, CAS # | Gene ID: 16187 |
|---|
| Catalog # | ABIN2018102 |
|---|
| Price | |
|---|
| Order / More Info | Interleukin 3 (Colony-Stimulating Factor, Multiple) (Il3) (AA 33-166) (Active) protein from ANTIBODIES-ONLINE GmbH |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|