| 产品详情 |
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| Product Name | Interleukin 1 eta (FIL1h) (AA 5-157), (Isoform 2) protein |
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| Description | IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination. |
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| Size | 10 µg |
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| Concentration | n/a |
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| Applications | SDS-PAGE (SDS) |
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| Other Names | 2310043N20Rik|Il36b|FIL1|FIL1-(ETA)|FIL1H|FILI-(ETA)|IL-1F8|IL-1H2|IL1-ETA|IL1F8|IL1H2|Il1f8 |
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| Gene, Accession, CAS # | Gene ID: 27177 |
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| Catalog # | ABIN2745714 |
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| Price | |
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| Order / More Info | Interleukin 1 eta (FIL1h) (AA 5-157), (Isoform 2) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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