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| Product Name | Recombinant Human Polycomb complex protein BMI-1 (BMI1), partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 56.4kDa. Partial: 1-250aa. N-terminal GST-tagged. Homo sapiens (Human). Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin rodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Polycomb group RING finger protein 4RING finger protein 51 |
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| Gene, Accession, CAS # | BMI1, UniProt: P35226 |
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| Catalog # | RPC24028 |
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| Order / More Info | Recombinant Human Polycomb complex protein BMI-1 (BMI1), partial from BIOMATIK |
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| Product Specific References | n/a |
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