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| Product Name | Myriocin (ISP-1) |
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| Description | Purity >98%. A fungal metabolite with potent immunosuppressant activity that is 10-100 fold more compared to Cyclosporin A . It inhibits serine palmitoyltransferase (Ki = 0.28 nM) blocking the synthesis of ceramide. It was found to suppress melanoma cell proliferation by cell cycle arrest at the G 2/M phase through decreased sphingolipid levels and increased p53 and p21 (waf1/cip1) expression. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (2S,3R,4R,6E)-2-Amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acid |
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| Gene, Accession, CAS # | CAS: 35891-70-4 |
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| Catalog # | LS-H3135 |
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| Order / More Info | Myriocin (ISP-1) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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