| 产品详情 |
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| Product Name | Minichromosome Maintenance Deficient 4 (MCM4) peptide |
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| Description | The protein encoded by MCM4 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRkDaC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcript variants encoding the same protein have been reported. |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (IHC),Blocking Peptide (BP) |
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| Other Names | cb1025|fc12c09|fj85g09|hm:zeh1616|wu:fc12c09|wu:fj85g09|zeh1616|CDC21|CDC54|NKCD|NKGCD|P1-CDC21|hCdc21|Mcmd4|19G|AI325074|AU045576|Cdc21|mKIAA4003|mcdc21 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | ABIN939711 |
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| Price | |
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| Order / More Info | Minichromosome Maintenance Deficient 4 (MCM4) peptide from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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| 产品资料 |
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