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| Product Name | Rac1 G15A Agarose Beads (Active Rac-GEF) |
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| Description | Purity >90% by SDS-PAGE and Coomassie blue staining. Specifically interacts and precipitaes active Rac-GEF from cell lysate. • Pull down the active form of Rac1-GEF• Colored for easy visualizationSmall GTP-binding proteins (or GTPases) are a family of proteins that serve as molecular regulators in signaling transduction pathways. Rac, a 21 kDa protein, belongs to the family of Rho GTPases regulating a variety of biological response pathways that include cell motil |
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| Size | 0.8 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Rac1 G15A Agarose Beads (Active Rac-GEF)] |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | MBS168525 |
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| Order / More Info | Rac1 G15A Agarose Beads (Active Rac-GEF) from MYBIOSOURCE INC. |
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| Product Specific References | 1. Arthur, W.T., Ellerbroek, S.M., Der, C.J., and Burridge K. (2002) J. Biol. Chem. 277, 42964-42972 2. Garcia-Mata R., Wennerberg, K., Arthur, W.T., Noren, N.K., Ellenbroek, S.M., and Burridge K. (2006) Methods Enzymol. 406, 425-437. 1. Wu, C. Y. et al. (2014). PI3K regulation of Rac1 Is required for KRAS-Induced pancreatic tumorigenesis in mice. Gastroenterology.147:1405-1416. 2. Colacios, C. et al. (2011). The p.Arg63Trp polymorphism controls Vav1 functions and Foxp3 regulatory T cell develop |
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