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| Product Name | (±)12-HEPE |
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| Description | Purity >98%. (±)12-HEPE is produced by non-enzymatic oxidation of EPA. It contains equal amounts of 12(S)-HEPE and 12(R)-HEPE. The biological activity of (±)12-HEPE is likely mediated by one of the individual isomers, most commonly the 12(S) isomer in mammalian systems. 12-HEPE inhibits platelet aggregation with the same potency as 12-HETE, exhibiting IC50 values of 24 and 25 µM, respectively. These compounds are also equipotent as inhibitors of U46619-induced contraction of rat aorta (IC50 s = 8.6-8.8 µM). |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (±)-12-hydroxy-5Z,8Z,10E,14Z,17Z-eicosapentaenoic acid |
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| Gene, Accession, CAS # | CAS: 81187-21-5 |
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| Catalog # | LS-H5490 |
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| Order / More Info | (±)12-HEPE from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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