| Description | ENA-78 is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. ENA-78 is a chemoattractant for neutrophils. The Mouse homolog of ENA-78 is called LIX. The three naturally occurring variants of human ENA-78, ENA 5-78, ENA 9-78 and ENA 10-78, contain 74, 70, and 69 amino acid residues, respectively, and possess the same biological activity. ENA-78 contains the four conserved cysteine residues present in CXC chemokines, and also contains the 'ELR' motif common to CXC chemokine that bind to the CXCR1 and CXCR2 receptors. Alternative Names: ENA-78, ENA-78 protein, ENA 78, ENA 78 protein, Mouse protein, CXCL5 protein, LIX protein, ENA-78 protein, ENA78, Epithelial Neutrophil Activating Peptide-78 protein |
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