| 产品详情 |
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| Product Name | Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1) (AA 25-337) protein (His tag) |
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| Description | Fractalkine(CX3CL1) is a single-pass type I membrane protein and belongs to the intercrine delta family. It consists of an extracellular NH2-terminal domain, a mucin-like stalk, a transmembrane α helix, and a short cytoplasmic tail. CX3CL1 exists in two forms: as a membrane-anchored or as a shed 80-95K glycoprotein. Soluble CX3CL1 is generated by limited proteolysis on the cell surface, and a disintegrin and metallopeptidase 10 (ADAM10) and ADAM17/tumor necrosis factor-α-converting enzyme (ADAM17/TACE) participate in this shedding. It has been suggested that ADAM10 acts in the constitutive shedding, and ADAM17 acts in response to cell activation. The protein may play a role in regulating leukocyte adhesion and migration processes at the endothelium. |
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| Size | 10 µg |
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| Concentration | n/a |
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| Applications | SDS-PAGE (SDS) |
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| Other Names | CX3CL1|DKFZp459K117|Cx3C-rs1|Scyd1-rs1|Cx3c|Scyd1|AB030188|ABCD-3|AI848747|CX3C|Cxc3|D8Bwg0439e|C3Xkine|CXC3|CXC3C|NTN|NTT|SCYD1|fractalkine|neurotactin |
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| Gene, Accession, CAS # | Gene ID: 20312 |
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| Catalog # | ABIN1945328 |
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| Order / More Info | Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1) (AA 25-337) protein (His tag) from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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