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Product Name | SMAD Family Member 4 (SMAD4) (AA 1-552) protein (His tag) |
Description | SMAD4 is part of the SMAD family of proteins that mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. SMAD4 promotes the binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides the function of activation required for SMAD1 or SMAD2 to stimulate transcription acts as a tumor suppressor. SMAD4 is a target molecule for functional inactivation in cervical cancer. SMAD4 is an important biomarker for malignant transformation atakes part in inducing apoptosis by modulating Bcl-2/Bax balance Synonyms: JIP, DPC4, MADH4, SMAD-4, DPC-4, MADH-4, Mothers against decapentaplegic homolog 4, Mothers against DPP homolog 4, SMAD 4, hSMAD4, Deletion target in pancreatic carcinoma 4, SMAD4, SMAD family member 4 |
Size | 50 µg |
Concentration | n/a |
Applications | n/a |
Other Names | smad4|DPC4|JIP|MADH4|MYHRS|AW743858|D18Wsu70e|Madh4|XSmad4alpha|Xsmad4|dpc4|jip|madh4|xsmad4a |
Gene, Accession, CAS # | Gene ID: 4089 |
Catalog # | ABIN807005 |
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Order / More Info | SMAD Family Member 4 (SMAD4) (AA 1-552) protein (His tag) from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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