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| Product Name | Interleukin 22 (IL22) (Active) protein |
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| Description | Interleukin-22 (IL-22), also known as IL-10-related T cell-derived inducible factor (IL-TIF) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. Mouse IL-22 cDNA encodes a 179 amino acid residue protein with a putative 33 amino acids signal peptide that is cleaved to generate a 147 aa mature protein that shares approximately 79 % and 29 % aa sequence identity with human IL-22 and IL-10, respectively. IL-22 has been shown to activate STAT-1 and STAT-3 in several hepatoma cell lines and upregulate the production of acute phase proteins. IL-22 is produced by normal mouse T cells upon Con A activation. Mouse IL-22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL-22 may be involved in inflammatory responses. The functional IL-22 receptor complex consists of two receptor subunits, IL-22R (previously an orphan receptor named CRF2-9) and IL-10Rbeta (previously known as CRF2-4), belonging to the class II cytokine recep . Synonyms: IL-TIF, TIFa, IL-10-related T-cell-derived-inducible factor, IL-22, ILTIF, IL-D110, zcyto18, MGC79382, MGC79384, TIFIL-23. |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | IL-17D|IL-22|IL-27|IL27|IL-21|IL-D110|IL-TIF|ILTIF|TIFIL-23|TIFa|zcyto18|IL-22a|ILTIFa|Iltif|RGD1561292|interleukin-22 |
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| Gene, Accession, CAS # | Gene ID: 50929 |
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| Catalog # | ABIN805152 |
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| Order / More Info | Interleukin 22 (IL22) (Active) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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