| 产品详情 |
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| Product Name | Lonidamine |
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| Description | Purity >98%. Lonidamine, originally identified as a potent antispermatogenic agent, inhibits glycolysis though the inactivation of mitochondria-bound hexokinase. It can decrease oxygen consumption as well as aerobic and anaerobic glycolysis in Ehrlich ascites tumor cells with IC50 values of 90 and 45 µM, respectively. A role for lonidamine as a therapeutic for mitochondrial dysfunction has been explored in various disorders, including cancer, neurodegenerative and neuromuscular diseases, obesity, and diabetes. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-[(2,4-dichlorophenyl)methyl]-1H-indazole-3-carboxylic acid, AF 1890, DICA, Diclondazolic Acid |
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| Gene, Accession, CAS # | CAS: 50264-69-2 |
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| Catalog # | LS-H8514 |
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| Price | |
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| Order / More Info | Lonidamine from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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