| 产品详情 |
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| Product Name | Fumagillin |
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| Description | Purity >95%. Fumagillin is an antibiotic derived from the fungus A. fumigatus . It binds and inhibits methionine aminopeptidase-2 with an IC50 value of 10 nM. Fumagillin inhibits angiogenesis by impairing the growth of endothelial cells and altering gene expression. It also impairs microsporidial replication and can be used to treat both conjunctival and intestinal microsporidial infections in immunocompromised patients. Finally, fumagillin reduces diet-induced adipose tissue formation in mice, independent of its effects on angiogenesis. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2E,4E,6E,8E-decatetraenedioic acid, 1-[(3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-buten-1-yl)-2-oxiranyl]-1-oxaspiro[2.5]oct-6-yl] ester, Amebacilin, NSC 9168 |
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| Gene, Accession, CAS # | CAS: 23110-15-8 |
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| Catalog # | LS-H7859 |
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| Price | |
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| Order / More Info | Fumagillin from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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