| 产品详情 |
| Edit |   |
|---|
| Product Name | Fumagillin (high purity) |
|---|
| Description | Purity >98% by NMR. Meroterpenoid antibiotic. Anticancer, antimicrobial, antimalarial and amoebicidal compound. Potent, selective and covalent inhibitor of methionine aminopeptidase-2 (MetAP2). Anti-angiogenic by impairing the growth of endothelial cells and altering gene expression. Inhibits endothelial cell proliferation in vitro and tumor-induced angiogenesis in vivo. Suppresses the HIV-1 infection of human macrophages through the inhibition of HIV-1 viral protein R (Vpr) activity. Inhibits neovascularization and might be useful in non-tumor diseases such as diabetic retinopathy, arthritis and psoriasis, which involve neovascularisation processes. Reduces diet-induced adipose tissue formation in mice, independent of its effects on angiogenesis. |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | Amebacilin, Fugilin, Fumadil B, Fumidil, NSC9168, U5762 |
|---|
| Gene, Accession, CAS # | CAS: 23110-15-8 |
|---|
| Catalog # | LS-H815 |
|---|
| Price | |
|---|
| Order / More Info | Fumagillin (high purity) from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|