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Antigenic Specificity | PDK4 |
Clone | 5C2 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 100ul |
Concentration | n/a |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PDK4 (5C2) Monoclonal Antibody. • Target Background: Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. Inhibition of pyruvate dehydrogenase decreases glucose utilization and increases fat metabolism in response |
Immunogen | Purified His-tagged PDK4 protein(Fragment) was used to produced this monoclonal antibody. |
Other Names | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial; Pyruvate dehydrogenase kinase isoform 4; PDK4; PDHK4 |
Gene, Accession # | Gene ID: 5166, SwissProt: Q16654 |
Catalog # | bsm-51108M |
Price | |
Order / More Info | PDK4 Antibody from BIOSS ANTIBODIES |
Product Specific References | n/a |