产品详情 |
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Antigenic Specificity | PDK1 |
Clone | 4A11 |
Host Species | Mouse |
Reactive Species | human, mouse, nonhuman primate, rat |
Isotype | IgG1 |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Flow Cytometry: 1/200 - 1/400, Immunocytochemistry: 1:200-1:1000, Immunofluorescence: 1/200 - 1/1000, Immunohistochemistry: 1/200 - 1/1000, Western Blot: 1/500 - 1/2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PDK1 Monoclonal Antibody (4A11). Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Tissue specificity: Expressed predominantly in the heart. |
Immunogen | n/a |
Other Names | mitochondrial pyruvate dehydrogenase, lipoamide, kinase isoenzyme 1; pyruvate dehydrogenase kinase, isoenzyme 1 |
Gene, Accession # | Entrez: 116551, 228026, 5163; Uniprot: Q15118, Q63065, Q8BFP9 |
Catalog # | MA5-15797 |
Price | |
Order / More Info | PDK1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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