| 产品详情 |
| Edit |   |
|---|
| Product Name | Zibotentan |
|---|
| Description | A selective ETA receptor antagonist (IC50s = 21 and >10,000 nM for human recombinant ETA and ETB, respectively); inhibits ET-1-induced growth of HEY, OVCA 433, SKOV3, and A2780 cells in vitro; reduces ET-1-induced expression of MMP-2, MMP-9, VEGF, COX-1 and COX-2 in HEY cells; reduces tumor growth in an HEY mouse xenograft model in a dose-dependent manner (10-50 mg/kg per day) |
|---|
| Size | 25 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | ZD 4054 |
|---|
| Gene, Accession, CAS # | CAS: 186497-07-4 |
|---|
| Catalog # | 23702-25 |
|---|
| Price | |
|---|
| Order / More Info | Zibotentan from CAYMAN CHEMICAL COMPANY |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|