| 产品详情 |
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| Product Name | Amyloid beta (A4) Precursor Protein (APP) (AA 1-42) peptide |
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| Description | This peptide is well suited to the quantitative determination of A 42 peptide. Alzheimer's disease (AD) is characterized by the presence of extracellular plaques and intracellular neurofibrillary tangles (NFTs) in the brain. The major protein component of these plaques is beta amyloid peptide (A), a 40- to 43- amino-acid peptide cleaved from amyloid precursor protein by secretase (BACE) and a putative (gamma) secretase. Increased release of the `longer forms' of A peptide, A 42 and A 43, which have a greater tendency to aggregate than A 40, occurs in individuals expressing certain genetic mutations, expressing certain ApoE alleles or may other, still undiscovered factors. Solubility: Insoluble in water, may be dissolved in any buffer with pH greater than 9 - 15 mg/ml for click peptide in water compared to 0.14 mg/ml for the native peptide. |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | APP|APP-like|APPL|Abeta|BcDNA:GH04413|CG7727|Dmel\\CG7727|EG:65F1.5|appl|aaa|abeta|abpp|ad1|appi|ctfgamma|cvap|pn2|AAA|ABETA|ABPP|AD1|APPI|CTFgamma|CVAP|PN-II|PN2|Abpp|Adap|Ag|Cvap|E030013M08Rik|betaApp|app|wu:fj34d10|wu:fk65e12|zgc:85740 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | ABIN987295 |
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| Price | |
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| Order / More Info | Amyloid beta (A4) Precursor Protein (APP) (AA 1-42) peptide from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 22403681, 24983378, 26204501 |
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