| 产品详情 |
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| Product Name | Tariquidar |
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| Description | Purity >98% by HPLC. Tariquidar is a potent, specific, noncompetitive inhibitor of P-glycoprotein (P-gp) (Kd = 5.1 nM). Tariquidar inhibits the ATPase activity of P-gp, suggesting that the modulating effect is derived from the inhibition of substrate binding, inhibition of ATP hydrolysis or both. At low concentrations, Tariquidar acts selectively as an inhibitor of P-gp and as a substrate of BCRP (breast cancer resistance protein). At much higher concentrations (=100 nM). Tariquidar acts as an inhibitor of both P-gp and BCRP. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | XR-9576,Tariquidar, N-[2-[[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]carbamoyl]-4,5-dimethoxyphenyl]quinoline-3-carboxamide, XR 9576, XR9576 |
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| Gene, Accession, CAS # | CAS: 206873-63-4 |
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| Catalog # | LS-H3397 |
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| Price | |
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| Order / More Info | Tariquidar from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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