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| Product Name | Recombinant Human Cold-inducible RNA-binding protein (CIRBP) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 45.6kDa. Full Length: 1-172aa. N-terminal GST-tagged. Homo sapiens (Human). Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | A18 hnRNP; Glycine-rich RNA-binding protein CIRP |
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| Gene, Accession, CAS # | CIRBP, UniProt: Q14011 |
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| Catalog # | RPC22965 |
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| Order / More Info | Recombinant Human Cold-inducible RNA-binding protein (CIRBP) from BIOMATIK |
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| Product Specific References | n/a |
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