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| Product Name | Recombinant Human Collagen alpha-1 (IV) chain (COL4A1), partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 40.9kDa. Partial: 1445-1669aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Type IV collagen is the major structural component of glomerular basent mbranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | n/a |
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| Gene, Accession, CAS # | COL4A1, UniProt: P02462 |
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| Catalog # | RPC21120 |
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| Order / More Info | Recombinant Human Collagen alpha-1 (IV) chain (COL4A1), partial from BIOMATIK |
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| Product Specific References | n/a |
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