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| Product Name | Recombinant Human Caspase-3 (CASP3), partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 20.6kDa. Partial: 29-175aa. N-terminal 6xHis-tagged. Homo sapiens (Human). Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly (ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory elent binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the mbrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1 |
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| Gene, Accession, CAS # | CASP3, UniProt: P42574 |
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| Catalog # | RPC25585 |
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| Order / More Info | Recombinant Human Caspase-3 (CASP3), partial from BIOMATIK |
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| Product Specific References | n/a |
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