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Product Name | Recombinant Rat Cytochrome P450 1B1 |
Description | 1-543aa; Full Length. MW: 64.62kD. Purity >90% as determined by SDS-PAGE. Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, retinoid and xenobiotics. Preferentially oxidizes 17beta-estradiol to the carcinogenic 4-hydroxy derivative, and a variety of procarcinogenic compounds to their activated forms, |
Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
Concentration | n/a |
Applications | n/a |
Other Names | [CYPIB1; Cytochrome P450RAP] |
Gene, Accession, CAS # | Cyp1b1, Gene ID: 25426, Accession: NP_037072.1 |
Catalog # | MBS1325163 |
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Order / More Info | Recombinant Rat Cytochrome P450 1B1 from MYBIOSOURCE INC. |
Product Specific References | Specificity determinants of CYP1B1 estradiol hydroxylation.Nishida C.R., Everett S., Ortiz de Montellano P.R.Mol. Pharmacol. 84:451-458(2013) |
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