| 产品详情 |
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| Product Name | EX-527 |
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| Description | Purity >98%. Mammalian sirtuin 1 (SIRT1) is a nicotinamide adenine dinucleotide-dependent histone deacetylase (HDAC) with roles in energy metabolism and inflammation. EX-527 is a cell-permeable, selective inhibitor of SIRT1 (IC50 = 98 nM). It inhibits other SIRTs only at much higher concentrations and has no effect on other HDACs. EX-527 has been used to investigate the relationship between SIRT1-mediated deacetylation of p53, p53 activity, and cell survival following DNA damage. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide |
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| Gene, Accession, CAS # | CAS: 49843-98-3 |
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| Catalog # | LS-H7741 |
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| Price | |
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| Order / More Info | EX-527 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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