| 产品详情 |
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| Product Name | Deoxyuridine Triphosphatase (DUT) peptide |
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| Description | DUT is an essential enzyme of nucleotide metabolism. This protein forms a ubiquitous, homotetrameric enzyme that hydrolyzes dUTP to dUMP and pyrophosphate. This reaction serves two cellular purposes: providing a precursor (dUMP) for the synthesis of thymine nucleotides needed for DNA replication, and limiting intracellular pools of dUTP. Elevated levels of dUTP lead to increased incorporation of uracil into DNA, which induces extensive excision repair mediated by uracil glycosylase. This repair process, resulting in the removal and reincorporation of dUTP, is self-defeating and leads to DNA fragmentation and cell death. |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (IHC),Blocking Peptide (BP) |
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| Other Names | BcDNA:LD08534|CG4584|Dmel\\CG4584|LD08534|UTPase|anon-SAGE:Wang-077|dUTPase|Tb07.27E10.390|dutpase|5031412I06Rik|5133400F09Rik|D2Bwg0749e|Dutp|PIP4 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | ABIN936446 |
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| Price | |
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| Order / More Info | Deoxyuridine Triphosphatase (DUT) peptide from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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