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| Product Name | Mouse IL-2RG Recombinant (CD132) |
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| Description | MW: 42,241 Da. Purity >97%, as determined by SDS-PAGE. Interleukin (IL) -2, IL-4, IL-7, IL-9 and IL-15 belong to a family of cytokines whose receptors share the common γ chain (γc). Despite some redundancy, these cytokines that signal through the γc (γccytokines) have essentially distinct and often critical effects in normal T-cell development, survival, proliferation and differentiation. Importantly, they have also been implicated, directly or indirectly, in T-cell leukemoge |
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| Size | 0.02 mg, 0.1 mg, 0.5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Mouse IL-2RG Recombinant; il-2RG; il2RG; CD132] |
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| Gene, Accession, CAS # | IL2RG, Gene ID: 16186, Accession: NP_038591.1 |
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| Catalog # | MBS553237 |
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| Order / More Info | Mouse IL-2RG Recombinant (CD132) from MYBIOSOURCE INC. |
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| Product Specific References | • il-21 is the primary Common gamma chain-binding cytokine required for human b-cell differentiation in vivo .Blood, Oct 2011; 10.1182/blood-2011-06-362533. • il-2r common -chain is epigenetically silenced by nucleophosphin-anaplastic lymphoma kinase (npm-alk) and acts as a tumor suppressor by targeting npm-alk .PNAS, Jul 2011; 108: 11977 - 11982. • a subpopulation of follicular lymphoma tumor infiltrating t cells shows suppressed Common gamma chain cytokine signaling. .Blood (ASH |
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