产品详情 |
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Antigenic Specificity | DENND1B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Immunohistochemistry: 1:200-1:500, Western Blot: 0.4 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DENND1B Polyclonal Antibody. Clathrin (see MIM 118955)-mediated endocytosis is a majormechanism for internalization of proteins and lipids. Members ofthe connecdenn family, such as DENND1B, function as guaninenucleotide exchange factors (GEFs) for the early endosomal smallGTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptorprotein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35activation with the clathrin machinery. |
Immunogen | n/a |
Other Names | RP11-53I24.2, C1ORF18, C1orf218, FAM31B, DENN domain-containing protein 1B, connecdenn 2, family with sequence similarity 31, member B |
Gene, Accession # | Entrez: 163486; Uniprot: Q6P3S1 |
Catalog # | PA5-60036 |
Price | |
Order / More Info | DENND1B Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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