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| Product Name | Recombinant Mouse SHP2 / PTPN11 Protein (His tag) |
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| Description | MW: 68,035 Da. Purity >90 % as determined by SDS-PAGE. Background: SHP2, also known as PTPN11, belongs to the protein-tyrosine phosphatase (PTP) family, non-receptor class 2 subfamily. PTPs catalyze the removal of phosphate groups from tyrosine residues by the hydrolysis of phosphoric acid monoesters. They dephosphorylate EGFR, JAK2 and TYK2 kinases, promoting oncogenic transformation. SHP2 is widely expressed, with highest levels in heart, brain, and skeletal muscle. SHP2 acts downstream of var |
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| Size | 0.1 mg, 0.2 mg |
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| Concentration | n/a |
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| Applications | The recombinant mouse PTPN11 comprises 604 amino acids and has a predicted molecular mass of 69.5 kDa. The apparent molecular mass of the protein is approximately 65 kDa in SDS-PAGE under reducing conditions due to glycosylation. |
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| Other Names | [PTPN11] |
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| Gene, Accession, CAS # | SHP2 / PTPN11, Gene ID: 19247, Accession: NP_001103462.1 |
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| Catalog # | MBS2546971 |
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| Price | |
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| Order / More Info | Recombinant Mouse SHP2 / PTPN11 Protein (His tag) from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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