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Antigenic Specificity | Ly-6G/Ly-6C |
Clone | RB6-8C5 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2b |
Format | purified |
Size | 100 ug |
Concentration | n/a |
Applications | Flow Cytometry: 2-8 µg/mL, Functional Assay: Assay Dependent, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): Assay-Dependent, Immunoprecipitation: 1-2 µg/mL, Western Blot: 1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Ly-6G/Ly-6C Monoclonal Antibody (RB6-8C5). Ly6G is a component of the myeloid differentiation antigen Gr-1, together with Ly6C. Ly6G is a good marker for detection of peripheral neutrophils. Expression of Gr-1 in bone marrow correlates with granulocyte differentiation and maturation. Physiological role of Ly6G remains still unclear. Its treatment with antibodies in vivo leads to neutropenia and has inhibitory effect on local immune responses. |
Immunogen | n/a |
Other Names | Gr-1, Gr1, Ly-6G, ly-6G.1, lymphocyte antigen 6G |
Gene, Accession # | Entrez: 546644; Uniprot: P35461 |
Catalog # | MA1-10401 |
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Order / More Info | Ly-6G/Ly-6C Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 10670575, 10679002, 11427280, 11457550, 11698429, 12744902, 14615143, 14993252, 15122268, 15240716, 15265888, 15494516, 15551212, 15665725, 15731075, 16237077, 16278309, 16319726, 16365392, 16984263, 17158904, 17959178, 18400308, 18923845, 19346496, 22163019, 23665276, 24721775, 25053428, 27573814, 27601624, 27697499, 27731330, 27779193, 27783593, 27869817, 27882944, 28062503, 28254837, 2849552, 3584977, 8754857 |
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