产品详情 |
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Antigenic Specificity | Clostridium tetani Tetanus Toxin |
Clone | 14F5 |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1, kappa |
Format | purified |
Size | 200 µl |
Concentration | n/a |
Applications | ELISA: 1:8,000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Clostridium tetani Tetanus Toxin Monoclonal Antibody (14F5). Tetanus toxin is a neurotoxin produced by the vegetative spore of Clostridium tetani. The toxin causes tetanus, a disease that is characterised by prolonged contraction of skeletal muscle. World-wide, approximately 1 million cases of tetanus occurs annually, resulting in approximately 300,000 to 500,000 deaths, mostly in developing countries. The tetanus toxin has a molecular weight of approximately 150kDa and consists of a heavy chain (B-chain, 100kDa) and a light chain (A-chain, 50kDa) that are connected by a disulfide bond. The toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the ax |
Immunogen | n/a |
Other Names | C. tetani; Tetanus Toxin |
Gene, Accession # | n/a |
Catalog # | HYB 278-14-02 |
Price | |
Order / More Info | Clostridium tetani Tetanus Toxin Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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