| 产品详情 |
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| Product Name | MKT-077 |
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| Description | Purity >95%. MKT-077 is a cationic rhodacyanine dye that demonstrates antiproliferative activity against cancer cell lines (EC50 s = 1.4-2.2 µM in vitro ) through its ability to inhibit members of the heat shock protein 70 (Hsp70) family of molecular chaperones. It has been shown to bind to an allosteric site conserved in Hsp70 family members, interfering with ATP hydrolysis and abrogating the interaction of the chaperone with the tumor suppressor p53. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-ethyl-2-[[3-ethyl-5-(3-methyl-2(3H)-benzothiazolylidene)-4-oxo-2-thiazolidinylidene]methyl]-pyridinium, monochloride, FJ-776 |
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| Gene, Accession, CAS # | CAS: 147366-41-4 |
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| Catalog # | LS-H8720 |
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| Price | |
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| Order / More Info | MKT-077 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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